LIN28B antibody

Catalog No. ABIN7115883

This anti-LIN28B antibody is a Rabbit Polyclonal antibody detecting LIN28B in WB, ELISA, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for LIN28B antibody (ABIN7115883)

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIN28B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LIN28B Antibody

Purpose: LIN28B-specific antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: lin-28 homolog B

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for LIN28B

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Alternative Name: LIN28B

Background:

Synonyms: Protein lin-28 homolog B (Lin-28B)|LIN28B|CSDD2

Background: LIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA(miRNA) biogenesis by specifically binding the precursor let-7(pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells, however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78 % sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B.

UniProt: Q6ZN17